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                              Patient in Germany is world’s first to receive brachytherapy with Elekta’s new Venezia gynecological applicator

                              April 26, 2017
                              Applicator maximizes anatomical reach of therapeutic radiation for patients with advanced cervical cancer

                              A 51-year-old patient with advanced cervical cancer became the world’s first to receive brachytherapy assisted by Elekta’s Venezia™, a gynecological applicator designed to reach not only the cervix, but also disease that has spread to the parametrium and vagina. Cervical cancer is the third-most common cancer among women worldwide, with an annual incidence of 530,000 cases and 250,000 deaths. In the developing world, it is the leading cause of cancer death among women.[1]

                              Using Venezia™, physicians at Ludwig-Maximilians University of Munich (LMU Munich) successfully performed the interstitial brachytherapy procedure. Venezia allows clinicians to treat advanced stages of cervical cancer, such as stages IIIA and IIIB with vaginal and parametrial extensions, which previously required very specialized techniques, such as freehand needle placement.

                              “Getting the radiation to reach to disease extensions beyond the cervix has always been challenging with conventional brachytherapy applicators,” says Stefanie Corradini, MD, radiation oncologist at LMU Munich. “Venezia incorporates components that enable us to treat the cervix as well as the parametrium and vagina using a single applicator. We were able to treat this first patient’s disease extension in these anatomies by placing both parallel and oblique interstitial needles. With Venezia, we will have a very standardized way to treat cervical cancer and interstitial needle placement will be very reproducible.”

                              “The design of Venezia makes it intuitive to use,” adds LMU Munich’s Cornelius Maihöfer, MD. “Within just a few trial runs of applicator assembly, the team became proficient in handling Venezia.”

                              The two lunar-shaped ovoids of Venezia form a ring that when clicked together provide the ease of insertion of a tandem and ovoid applicator in combination with the dose distribution provided by a ring applicator. The ring creates a pear-shaped dose distribution, a proven dosimetry shape that matches the cervix and endometrium. To reach tumor extension beyond the cervix, the design also incorporates a perineal template for placement of parallel needles and holes in the ring for insertion of oblique needles.

                              “You could view Venezia as a hybrid brachytherapy applicator that combines the best characteristics of both ring and ovoid devices as well as an array of interstitial catheters that can be customized to each patient´s tumor anatomy,” Dr. Corradini says.

                              To learn more, visit www.elekta.com/Venezia.

                              1. Banerjee R, Kamrava M. Brachytherapy in the treatment of cervical cancer: a review. Int J Womens Health. 2014; 6: 555-564. Published online 2014 May 28. doi: 10.2147/IJWH.S46247.

                               

                              # # #

                              For further information, please contact:
                              Gert van Santen, Group Vice President Corporate Communications, Elekta AB
                              Tel: +31 653 561 242, Email: gert.vansanten@elekta.com
                              Time zone: CET: Central European Time
                               
                              Raven Canzeri, Global Public Relations Manager
                              Tel: +1 770 670 2524, Email: raven.canzeri@elekta.com
                              Time zone: EST: Eastern Standard Time
                               
                              About Elekta
                              Elekta is proud to be the leading innovator of equipment and software used to improve, prolong and save the lives of people with cancer and brain disorders. Our advanced, effective solutions are created in collaboration with customers, and more than 6,000 hospitals worldwide rely on Elekta technology. Our treatment solutions and oncology informatics portfolios are designed to enhance the delivery of radiation therapy, radiosurgery and brachytherapy, and to drive cost efficiency in clinical workflows. Elekta employs 3,600 people around the world. Headquartered in Stockholm, Sweden, Elekta is listed on NASDAQ Stockholm. www.elekta.com

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                              Important Safety Information: Radiation therapy is not appropriate for all patients. Radiation treatments may cause side effects that can vary depending on the part of the body being treated. In some patients, they can be severe. Treatment sessions may vary in complexity and time. Refer to individual product labeling (instructions for use) for more complete information on product safety and effectiveness for its intended use.